Monday, November 28, 2016

Effect of low frequency magnetic fields on melanoma: tumor inhibition and immune modulation

Results: The growth of B16-F10 cells was inhibited after exposure to the LF-MF. The inhibition was related to
induction of cell cycle arrest and decomposition of chromatins. Moreover, the LF-MF prolonged the mouse survival
rate and inhibited the proliferation of B16-F10 in melanoma metastasis mice model. Furthermore, the LF-MF
modulated the immune response via regulation of immune cells and cytokine production. In addition, the number
of Treg cells was decreased in mice with the LF-MF exposure, while the numbers of T cells as well as dendritic cells
were significantly increased.
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