5. Summary and Conclusions
In recent years, an abundance of research papers, review papers, and books has been published describing the possible physical and biological interactions of magnetic fields.Considering these articles comprehensively, the conclusions are as follows: the primary cause of changes in cells after incubation in external SMF is disruption of free radical metabolism and elevation of their concentration. Such disruption causes oxidative stress and, as a result, damages ion channels, leading to changes in cell morphology and expression of different genes and proteins and also changes in apoptosis and proliferation. Moreover, based on available data, it was concluded that exposure to SMFs alone has no or extremely small effects on cell growth and genetic toxicity regardless of the magnetic density. However, in combination with other external factors such as ionizing radiation and some chemicals such as cadmium, there is evidence strongly suggesting that an SMF modifies their effects. Effects of SMFs on apoptosis are a potentially interesting phenomenon. However, these effects often depended on a cell type and were not found in various types of cells. Many researchers have observed the effects of SMFs on tumor cells, particularly the inhibiting effects. In order to reduce the toxicity and resistance of single anticancer drugs, a variety of unified treatments were required. The synergy of magnetic fields and anticancer drugs was one of the methods. It provides a new strategy for the effective treatment of cancer.
These studies provide valuable insight into the phenomenon of biomagnetism and open new avenues for the development of new medical applications. Further studies are necessary to explore the mechanisms of the SMF action in more detail.
https://www.hindawi.com/journals/bmri/2013/602987/
No comments:
Post a Comment