On the function of DNA magnetism

Although magnetism of DNA in strong fields is well established, it is not commonly considered magnetic in natural weak fields. SInce the behavior of strings of magnetic balls resembles some of DNA behaviors such as in replication and transcription, we hypothesize that DNA is magnetic and that DNA strands are magnetized in antiparallel orientation. We hypothesise that magnetism of DNA is based on ring currents of pi electrons in its bases. We hypothesize that ring currents are fueled by heat, enzymes or active forms of water. Accordingly, we proposed a helical model of magnetic lines in DNA. We also suggested a new way how the magnetic field in DNA may oscillate and that these oscillations will be sequence dependent. We suggest that collective oscillations of interspersed and periodic repetitive DNA sequences could contribute to electromagnetic communications between the cells and creation of Gurwitch morphogenic field. We suggest that primary cilium may be an antenna for sending and receiving electromagnetic oscillations by the genome.
https://www.researchgate.net/publication/323676547_On_the_function_of_DNA_magnetism

Related Non-Scientific Article, pls disregard if not applicable

Prophet or profit? Nikola Tesla’s vision vs J.P. Morgan’s greed 
https://ahtribune.com/opinion/426-nikola-tesla-j-p-morgan.html

Photo-Magnetic Irradiation-Mediated Multimodal Therapy of Neuroblastoma Cells Using a Cluster of Multifunctional Nanostructures.

Abstract

The use of high intensity chemo-radiotherapies has demonstrated only modest improvement in the treatment of high-risk neuroblastomas. Moreover, undesirable drug specific and radiation therapy-incurred side effects enhance the risk of developing into a second cancer at a later stage. In this study, a safer and alternative multimodal therapeutic strategy involving simultaneous optical and oscillating (AC) magnetic field stimulation of a multifunctional nanocarrier system has successfully been implemented to guide neuroblastoma cell destruction. This novel technique permitted the use of low-intensity photo-magnetic irradiation and reduced the required nanoparticle dose level. The combination of released cisplatin from the nanodrug reservoirs and photo-magnetic coupled hyperthermia mediated cytotoxicity led to the complete ablation of the B35 neuroblastoma cells in culture. Our study suggests that smart nanostructure-based photo-magnetic hybrid irradiation is a viable approach to remotely guide neuroblastoma cell destruction, which may be adopted in clinical management post modification to treat aggressive cancers.

https://www.ncbi.nlm.nih.gov/pubmed/30274306

An Ion Channel Database with Small Molecule Modulators and Tissue Expression Information

The emerging field of bioelectricity has revealed numerous new roles for ion channels beyond the nervous system, which can be exploited for applications in regenerative medicine. Developing such biomedical interventions for birth defects, cancer, traumatic injury, and bioengineering first requires knowledge of ion channel targets expressed in tissues of interest. This information can then be used to select combinations of small molecule inhibitors and/or activators that manipulate the bioelectric state. Here, we provide an overview of electroceutical design environment (EDEn), the first bioinformatic platform that facilitates the design of such therapeutic strategies. This database includes information on ion channels and ion pumps, linked to known chemical modulators and their properties. The database also provides information about the expression levels of the ion channels in over 100 tissue types. The graphical interface allows the user to readily identify chemical entities that can alter the electrical properties of target cells and tissues.

https://www.researchgate.net/publication/329563722_EDEn_-_Electroceutical_Design_Environment_An_Ion_Channel_Database_with_Small_Molecule_Modulators_and_Tissue_Expression_Information

A quantum theory of disease, including cancer and aging

Abstract

A unique, non-invasive, holistic paradigm is presented for amelioration of aging and associated pathophysiologic conditions based upon biological piezoelectricity. The capacity for biostructures to amplify weak electromagnetic (EM) triggers through photon-phonon transductions may permit target-specific magnetic resonance energies to renormalize structural and functional integrity of critical biomolecules, such as telomeres, neurotransmitters, immunogenic transmissible microbiological agents, enzymes, peptide hormone trophic factors, transforming DNA segments… etc.  Amelioration of the aging process and the effects thereof, including potentialities for palliation of a diversity of conditions may be possible, utilizing nonionizing physiologic PicoTesla electromagnetic fields. Various quantum phenomena are hypothesized as underpinning mechanisms for both normal and diseased conditions, including piezoelectricity, cyclotron resonance, the Quantum Hall Effect, and magnetic resonance; leading to a discussion of biological fission, fusion, and super conduction in neoplasia. A new particle-wave equation is presented for calculating bio-interaction energies set in dual resonance with intrinsic energies of target masses, to induce quantum transpositional states therein restoring biological order; with concomitant reduction of immunogenic quantum state entropy in selective magnetic domains. Experimental studies demonstrating fundamental positive changes in biological models are discussed in support of this non-significant risk methodology. Such changes include electromagnetic modulation of autonomic nervous system (ANS) tonicity, regeneration of nerve ultrastructure in concert with restoration of functionality, diminished viability and/or proliferation rate in human mammary carcinoma cells, and positive clinical studies in neurological disorders such as Parkinson’s disease. Indeed, it appears that a new frontier in biology and medicine is being manifested through advances in electrophysiology, promising hope for palliation of the human condition in aging and disease. 

https://www.oatext.com/A-quantum-theory-of-disease-including-cancer-and-aging.php

Explanation of Osteoblastic Differentiation of Stem Cells by Photo Biomodulation Using the Resonant Recognition Model

Differentiation of stem cells into different tissues is a promising approach to treat a large number of diseases, as well as for tissue transplantation and repair. It has been shown that parathyroid hormone, similarly to stromal self-derived factor, and the radiation of specific electromagnetic frequencies of blue and green light, can encourage stem cell differentiation into osteoblasts. Here, we analysed parathyroid hormone, its receptor and stromal self-derived factor using the Resonant Recognition Model, which proposes that protein function is based on specific frequencies of electromagnetic radiation within ultraviolet , visible, infra-red and far infra-red light. The purpose of this research is to predict the characteristic frequencies related to parathyroid hormone activities, particularly differentiation of stem cells into osteoblasts. We have found that the most effective wavelength for stem cell differentiation would be 502 nm, which is between 420 nm and 540 nm, already experimentally proven to be effective in stimulating osteoblast differentiation. Thus, we propose that wavelength radiation of 502 nm will be even more efficient for differentiation of stem cells into osteoblasts.
https://www.researchgate.net/publication/333103727_Explanation_of_Osteoblastic_Differentiation_of_Stem_Cells_by_Photo_Biomodulation_Using_the_Resonant_Recognition_Model

International Commission on Non-Ionizing Radiation Protection - Guidelines

As an independent organization, the International Commission on Non-Ionizing Radiation Protection (ICNIRP) provides scientific advice and guidance on the health and environmental effects of non-ionizing radiation (NIR) to protect people and the environment from detrimental NIR exposure.
NIR refers to electromagnetic radiation such as ultraviolet, light, infrared, and radiowaves, and mechanical waves such as infra- and ultrasound. In daily life, common sources of NIR include the sun, household electrical appliances, mobile phones, Wi-Fi, and microwave ovens.
https://www.icnirp.org/en/home/index.html

Weak magnetic fields alter stem cell–mediated growth

Abstract

Biological systems are constantly exposed to electromagnetic fields (EMFs) in the form of natural geomagnetic fields and EMFs emitted from technology. While strong magnetic fields are known to change chemical reaction rates and free radical concentrations, the debate remains about whether static weak magnetic fields (WMFs; <1 mT) also produce biological effects. Using the planarian regeneration model, we show that WMFs altered stem cell proliferation and subsequent differentiation via changes in reactive oxygen species (ROS) accumulation and downstream heat shock protein 70 (Hsp70) expression. These data reveal that on the basis of field strength, WMF exposure can increase or decrease new tissue formation in vivo, suggesting WMFs as a potential therapeutic tool to manipulate mitotic activity.

https://advances.sciencemag.org/content/5/1/eaau7201