Radiofrequency radiation reshapes tumor immune microenvironment into antitumor phenotype in pulmonary metastatic melanoma

 We conclude that noninvasive RFR exposure induces antitumor remodeling of the TIME, leading to inhibition of tumor progression, which provides a promising novel strategy for TIME priming and potential combination with cancer immunotherapy.

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Pulsed Electromagnetic Fields (PEMFs) Trigger Cell Death and Senescence in Cancer Cells

 Abstract

The currently available anti-cancer therapies, such as gamma-radiation and chemotherapeutic agents, induce cell death and cellular senescence not only in cancer cells but also in the adjacent normal tissue. New anti-tumor approaches focus on limiting the side effects on normal cells. In this frame, the potential anti-tumor properties of Pulsed Electromagnetic Fields (PEMFs) through the irradiation of breast cancer epithelial cells (MCF-7 and MDA-MB-231) and normal fibroblasts (FF95) were investigated. PEMFs had a frequency of 8 Hz, full-square wave type and magnetic flux density of 0.011 T and were applied twice daily for 5 days. The data collected showcase that PEMF application decreases the proliferation rate and viability of breast cancer cells while having the opposite effect on normal fibroblasts. Moreover, PEMF irradiation induces cell death and cellular senescence only in breast cancer cells without any effect in the non-cancerous cells. These findings suggest PEMF irradiation as a novel, non-invasive anti-cancer strategy that, when combined with senolytic drugs, may eliminate both cancer and the remaining senescent cells, while simultaneously avoiding the side effects of the current treatments.

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Density Based Characterization of Mechanical Cues on Cancer Cells Using Magnetic Levitation

 How interesting:

A magnetic levitation device is developed (i.e., MagDense platform) where cells are levitated in a magnetic gradient allowing them to equilibrate to a levitation height that corresponds to their unique cellular density. In application of this system, MDA-MB-231 breast and A549 lung cancer cells are cultured and overall differences in cell density are observed in response to increasing collagen fiber density. 

Link to paper

Red light therapy improves glucose metabolism

 You may wonder why I post an article about light therapy, it's because light is another form of electromagnetism:

The red light can penetrate through the skin and positively impact the mitochondria within the body’s cells, helping to create more energy and allowing the cells to function better and repair themselves.

Co-lead study author Dr. Michael Powner, senior lecturer in neurobiology in the School of Health & Psychological Sciences at City University London said they decided to look at red light therapy as a way to help control blood sugar levels after reading a study from 2019Trusted Source highlighting that sunlight exposure could correlate with improved glucose metabolism.

“We explored this in bumblebees nd found that red light reduced systemic glucose after feeding,” Dr. Powner told Medical News Today. “This latest study clearly shows a translation of this to humans.”

“Red light is absorbed by mitochondria and helps them produce more energy,” he explained.

“It lubricates the energy-making machine. But in producing more energy this way they need more raw material and this is largely glucose. They take this out of the blood.”

Link to article

Related, see also

Infoceuticals and imprinting may exert positive biological effects on cellular physiology.

 Abstract:

Living organisms, from the simplest organization to the more complex, all share the requirement

of energy in order to perform basic functions that sustain life and ensure its continuity. Cellular

physiology requires complex mechanisms to maintain homeostasis that are activated when

normal parameters change. Ancient medical practices like acupuncture suggest that many of the

human health impairments occur because of an energetic imbalance. In this regard, NES Health

has developed the concept of "Infoceuticals" -- remedies designed to restore the body's energetic

balance, or the means by which it is powered and communicates wirelessly. These remedies may

be administered through a special preparation of mineralized water ("imprinted" with photons

and magnetic fields), or imprinted directly into the body via electronic equipment. In this report,

we used a multicellular platform to determine the effect on cellular physiology of diverse

Infoceuticals both in liquid form and through direct imprinting. We observed unique and cellspecific effects in terms of cellular membrane structure, mitochondrial function, oxidative stress,

and viral infection protection. These findings aim to provide basic science insights to the process

of understanding the underlying phenomena that take place after Infoceutical treatments.

Link to paper

Stanford School of Medicine Tumor Treating Fields

 ROOT, Switzerland–(BUSINESS WIRE)– Novocure (NASDAQ: NVCR) today announced it has entered into an agreement with Stanford University to establish the Stanford School of Medicine Tumor Treating Fields (TTFields) Research Program. The program is intended to support both preclinical studies and clinical trials with TTFields, electric fields that exert physical forces to kill cancer cells via a variety of mechanisms.

Link to Press Release