Physicists could do the 'impossible': Create and destroy magnetic fields from afar

Physicists could do the 'impossible': Create and destroy magnetic fields from afar | Live Science

Scientists have figured out a way to create and cancel magnetic fields from afar. 

The method involves running electric current through a special arrangement of wires to create a magnetic field that looks as if it came from another source. This illusion has real applications: Imagine a cancer drug that could be delivered directly to a tumor deep in the body by capsules made of magnetic nanoparticles. It's not possible to stick a magnet in the tumor to guide the nanoparticles on their journey, but if you could create a magnetic field from outside the body that centered right on that tumor, you could deliver the drug without an invasive procedure. 

The strength of a magnetic field decreases with distance from the magnet, and a theorem proven in 1842, Earnshaw's Theorem, says that it's not possible to create a spot of maximum magnetic field strength in empty space.

Another use might be improving transcranial magnetic stimulation, which uses magnets to stimulate neurons in the brain to treat depression. Being able to control magnetic fields at a distance could improve the targeting of transcranial magnetic stimulation, so that doctors could better focus on particular regions in the human brain.  

Electrochemotherapy

Electrochemotherapy is gaining recognition as an effective local therapy that uses systemically or intratumorally injected bleomycin or cisplatin with electroporation as a delivery system that brings drugs into the cells to exert their cytotoxic effects. Preclinical work is still ongoing, testing new drugs, seeking the best treatment combination with other treatment modalities, and exploring new sets of pulses for effective tissue electroporation. The applications of electrochemotherapy are being fully exploited in veterinary oncology, where electrochemotherapy, because of its simple execution, has a relatively good cost–benefit ratio and is used in the treatment of cutaneous tumors. In human oncology, electrochemotherapy is fully recognized as a local therapy for cutaneous tumors and metastases. Its effectiveness is being explored in combination with immunomodulatory drugs. However, the development of electrochemotherapy is directed into the treatment of deep-seated tumors with a percutaneous approach. Because of the vast number of reports, this review discusses the articles published in the past 5 years.

 https://www.liebertpub.com/doi/full/10.1089/bioe.2019.0028