Wednesday, March 14, 2018

Mechanisms and therapeutic effectiveness of pulsed electromagnetic field therapy in oncology

PEMFs have also an immunomodulatory effect, as supported by in vivo evidence showing an increase in tumor necrosis factor alpha levels that induce an anti-tumoral response, leading to the activation of a proapoptotic pathway induced by caspase-8 interaction with Fas-associated death domain, in the spleen of the murine melanoma mouse model after a 16-day therapy [78]. Changes in blood pressure, skin electrical resistance, and pulse amplitude in 163 oncology patients exposed to tumor-specific PEMF frequencies have also been reported suggesting that PEMF therapy does not only target neoplastic cells, but may also have systemic effects [15]. However, long-term PEMF treatment in HCC patients is not toxic, confirming the safety of PEMF therapy that employs 100,000 times lower frequencies if compared with radiofrequency ablation that is also employed for treatment of HCC
http://onlinelibrary.wiley.com/doi/10.1002/cam4.861/full

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