Friday, September 27, 2019

The variable electric field of the membrane /Questioning the HodgkinHuxley model

Hodgkin and Huxley built their theoretical model of initiation and propagation of action potential on the work of their predecessors but also that of their contemporaries.

Bernstein was the initiator of membrane theory but Hodgkin, Katz and especially Goldman sought to improve it.

The integration of the constant electric field should have allowed a better knowledge and computation of the membrane potential.

The study of the variations in the electric field that would exist through the membrane brings harsh contradictions in the hypotheses of the HH model.

Link to Article

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